Publications
Highlights
Current and past lab members are highlighted in bold
Yu Liu, Ganka Bineva-Todd, Richard Meek, Laura Mazo, Beatriz Piniello, Olga Moroz, Nadima Begum, Andre Ohara, Chloe Roustan, Sara Tomita, Svend Kjaer, Karen Polizzi, Carme Rovira, Gideon Davies, Benjamin Schumann
Expanding the repertoire of GalNAc analogues for cell-specific bioorthogonal tagging of glycoprotein
ChemRxiv, 2024
ChemRxiv, 2024
Abdul Zafar, Sandhya Sridhar, Ganka Bineva-Todd, Anna Cioce, Nadia Abdulla, Vincent Chang, Stacy Malaker, David Hewings, Benjamin Schumann
Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells
bioRxiv, 2023
bioRxiv, 2023
Zhen Li, Lucia Di Vagno, Aisling Ni Cheallaigh, Douglas Sammon, David C Briggs, Nara Chung, Vincent Chang, Keira E Mahoney, Anna Cioce, Lloyd D Murphy, Yen-Hsi Chen, Yoshiki Narimatsu, Rebecca L Miller, Lianne I Willems, Stacy A Malaker, Gavin J Miller, Erhard Hohenester, Benjamin Schumann
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern
ACS Central Science, 2023
ACS Central Science, 2023
Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells
STAR Protocols, 2023
STAR Protocols, 2023
Benefits of chemical sugar modifications introduced by click chemistry for glycoproteomic analyses
Journal of the American Society for Mass Spectrometry, 2021
Journal of the American Society for Mass Spectrometry, 2021
Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase
ACS Chemical Biology 2021
ACS Chemical Biology 2021
Generating orthogonal glycosyltransferase and nucleotide sugar pairs as next-generation glycobiology tools
Current Opinion in Chemical Biology, 2021
Current Opinion in Chemical Biology, 2021
Anna Cioce, Stacy A Malaker, Benjamin Schumann
Mia Zol-Hanlon, Benjamin Schumann
Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation
PNAS, 2020
PNAS, 2020
Marjoke F Debets, Omur Y Tastan, Simon P Wisnovsky, Stacy A Malaker, Nikolaos Angelis, Leonhard KR Moeckl, Junwon Choi, Helen Flynn, Lauren JS Wagner, Ganka Bineva-Todd, Aristotelis Antononopoulos, Anna Cioce, William M Browne, Zhen Li, David C Briggs, Holly L Douglas, Gaelen T Hess, Anthony J Agbay, Chloe Roustan, Svend Kjaer, Stuart M Haslam, Ambrosius P Snijders, Michael C Bassik, WE Moerner, Vivian SW Li, Carolyn R Bertozzi, Benjamin Schumann
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
Molecular Cell, 2020
Molecular Cell, 2020
Benjamin Schumann, Stacy Alyse Malaker, Simon Peter Wisnovsky, Marjoke Froukje Debets, Anthony John Agbay, Daniel Fernandez, Lauren Jan Sarbo Wagner, Liang Lin, Zhen Li, Junwon Choi, Douglas Michael Fox, Jessie Peh, Melissa Anne Gray, Kayvon Pedram, Jennifer Jean Kohler, Milan Mrksich, Carolyn Ruth Bertozzi
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
Molecular Cell, 2020
Molecular Cell, 2020
Benjamin Schumann, Stacy Alyse Malaker, Simon Peter Wisnovsky, Marjoke Froukje Debets, Anthony John Agbay, Daniel Fernandez, Lauren Jan Sarbo Wagner, Liang Lin, Zhen Li, Junwon Choi, Douglas Michael Fox, Jessie Peh, Melissa Anne Gray, Kayvon Pedram, Jennifer Jean Kohler, Milan Mrksich, Carolyn Ruth Bertozzi
All Publications
Douglas Sammon, Anja Krueger, Marta Busse-Wicher, , Rhodri Marc Morgan, Stuart M. Haslam, Benjamin Schumann, David C. Briggs, & Erhard Hohenester
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth
Oncogene, 2023
Oncogene, 2023
Jennifer Munkley, Emma Scott, Kirsty Hodgson, Beatriz Calle, Helen Turner, Kathleen Cheung, Abel Bermudez, Fernando Marques, Hayley Pye, Edward Christopher Yo, Khirul Islam, Htoo Zarni Oo, Urszula L McClurg, Laura Wilson, Huw Thomas, Fiona M Frame, Margarita Orozco-Moreno, Kayla Bastian, Hector M Arredondo, Chloe Roustan, Melissa Anne Gray, Lois Kelly, Aaron Tolson, Ellie Mellor, Gerald Hysenaj, Emily Archer Goode, Rebecca Garnham, Adam Duxfield, Susan Heavey, Urszula Stopka-Farooqui, Aiman Haider, Alex Freeman, Saurabh Singh, Edward W Johnston, Shonit Punwani, Bridget Knight, Paul McCullagh, John McGrath, Malcolm Crundwell, Lorna Harries, Denisa Bogdan, Daniel Westaby, Gemma Fowler, Penny Flohr, Wei Yuan, Adam Sharp, Johann DeBono, Norman Maitland, Simon Wisnovsky, Carolyn Bertozzi, Rakesh Heer, Ramon Hurtado Guerrero, Mads Daugaard, Janne Leivo, Hayley Whitaker, Sharon Pitteri, Ning Wang, David Elliott, Benjamin Schumann
Butyrate differentiates permissiveness to Clostridioides difficile infection and influences growth of diverse C. difficile isolates
ASM Infection and Immunity, 2023
ASM Infection and Immunity, 2023
Daniel A Pensinger, Andrea T Fisher, Horia A Dobrila, William Van Treuren, Jackson O Gardner, Steven K Higginbottom, Matthew M Carter, Benjamin Schumann, Carolyn R Bertozzi, Victoria Anikst, Cody Martin, Elizabeth V Robilotti, JoMay Chow, Rachael H Buck, Lucy S Tompkins, Justin L Sonnenburg, Andrew J Hryckowian
Celebrating the Contributions of Carolyn Bertozzi to Bioorthogonal Chemistry and its Application to Glycoscience
Israel Journal of Chemistry, 2023
Israel Journal of Chemistry, 2023
Jessica R. Kramer, Matthew R. Pratt, Benjamin Schumann
4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase
ACS Chemical Biology, 2021
ACS Chemical Biology, 2021
Emma G Jackson, Giuliano Cutolo, Bo Yang, Nageswari Yarravarapu, Mary WN Burns, Ganka Bineva-Todd, Chloë Roustan, James B Thoden, Halley M Lin-Jones, Toin H van Kuppevelt, Hazel M Holden, Benjamin Schumann, Jennifer J Kohler, Christina M Woo, Matthew R Pratt
Junwon Choi, Lauren JS Wagner, Suzanne BPE Timmermans, Stacy A Malaker, Benjamin Schumann, Melissa A Gray, Marjoke F Debets, Megumi Takashima, Jase Gehring, Carolyn R Bertozzi
Paulina Kaplonek, Naeem Khan, Katrin Reppe, Benjamin Schumann, Madhu Emmadi, Marilda P Lisboa, Fei-Fei Xu, Adam DJ Calow, Sharavathi G Parameswarappa, Martin Witzenrath, Claney L Pereira, Peter H Seeberger
Development of an Efficacious, Semisynthetic Glycoconjugate Vaccine Candidate against Streptococcus pneumoniae Serotype 1
ACS Central Science, 2018
ACS Central Science, 2018
Benjamin Schumann, Katrin Reppe, Paulina Kaplonek, Annette Wahlbrink, Chakkumkal Anish, Martin Witzenrath, Claney L Pereira, Peter H Seeberger
Total Synthesis of a Densely Functionalized Plesiomonas shigelloides Serotype 51 Aminoglycoside Trisaccharide Antigen
JACS, 2018
JACS, 2018
Chunjun Qin, Benjamin Schumann, Xiaopeng Zou, Claney L Pereira, Guangzong Tian, Jing Hu, Peter H Seeberger, Jian Yin
A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine
Science Translational Medicine, 2017
Science Translational Medicine, 2017
Benjamin Schumann, Heung Sik Hahm, Sharavathi G Parameswarappa, Katrin Reppe, Annette Wahlbrink, Subramanian Govindan, Paulina Kaplonek, Liise-anne Pirofski, Martin Witzenrath, Chakkumkal Anish, Claney L Pereira, Peter H Seeberger
Nucleophile-Directed Stereocontrol Over Glycosylations Using Geminal-Difluorinated Nucleophiles
Angewandte Chemie International Edition, 2016
Angewandte Chemie International Edition, 2016
Benjamin Schumann, Sharavathi G Parameswarappa, Marilda P Lisboa, Naresh Kottari, Fabio Guidetti, Claney L Pereira, Peter H Seeberger
Chemical biology approaches to designing defined carbohydrate vaccines
Cell Chemistry & Biology, 2014
Cell Chemistry & Biology, 2014
Chakkumkal Anish, Benjamin Schumann, Claney Lebev Pereira, Peter H Seeberger
Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation
RSC Chemical Science, 2014
RSC Chemical Science, 2014
Benjamin Schumann, R Pragani, Chakkumkal Anish, Claney Lebev Pereira, Peter H Seeberger
Benjamin Schumann, Chakkumkal Anish, Claney L Pereira, Peter H Seeberger
A crucial role for Mim2 in the biogenesis of mitochondrial outer membrane proteins
Journal of Cell Science, 2012
Journal of Cell Science, 2012
Kai S Dimmer, Dražen Papić, Benjamin Schumann, Desirée Sperl, Katrin Krumpe, Dirk M Walther, Doron Rapaport